From pages 30-31 of the conference program (link).


Authors

Goodman, J. M.
Schaffelhofer, S.
Scherberger, H.


Abstract

Neurons in the frontoparietal cortical grasping network respond during both the execution and observation of an action. This observation has been used to support numerous theories linking motor control and cognition but remains poorly understood at the neuronal population level. To address this, we use chronic multi-electrode arrays to record simultaneously from neuronal populations in the macaque primary motor (M1), premotor (F5), and posterior parietal (AIP) cortices as animals either grasp a variety of different objects or observe a human subject doing the same. We find a lack of distinct functional neuronal classes in any of these cortical areas; instead, neurons exhibit a continuum of preferences for action and observation. The lack of clear neuron classes affirms that the link between action and observation may indeed be better understood in the framework of neuronal state space. Using targeted dimensionality reduction techniques, we find dimensions of neural activity that are shared between action and observation contexts, which decrease in prominence from AIP to F5 to M1. However, this shared activity does not include a shared representation of grip type, as assessed using classification methods that allow for response scaling and latency differences between the two contexts. We also fit linear dynamical systems to these data and fail to find a common dynamical structure underlying the disparate grip representations between action and observation. Activity during observation therefore lacks congruence with the precise grip-specific representations and dynamics seen during action. These results suggest that the link between action observation and action execution is weaker than anticipated in the frontoparietal network.